Mutual Funds Commodities Research Tax Planning IPO Our Team Contact Us  
Google
Web www.equitybulls.com
Stock Report

| More

ImmunoACT announces the approval of India's first CAR-T cell therapy, NexCAR19

Posted On: 2023-10-14 18:44:43 (Time Zone: IST)


Immunoadoptive Cell Therapy Private Limited ("ImmunoACT") received the marketing authorization approval of the first humanized CD19-targeted Chimeric Antigen Receptor T cell (CAR-T cell) therapy product for relapsed / refractory (r/r) B-cell lymphomas and leukemia in India.

NexCAR19 is an indigenously developed CD19 targeted CAR-T cell therapy. It is the firstof-its kind, a Made-in-India product and puts the nation firmly on the world map of advanced cell-and-gene therapies. ImmunoACT's vision is to provide a high quality and affordable CAR-T cell therapy platform to all sections of the society.

The multi-center Phase I/ II pivotal clinical trial, led by Dr Hasmukh Jain, was conducted with 60 patients of r/r B-cell lymphomas and leukemia. The clinical data indicates ~70% overall response rate (ORR). The safety profile in terms of cytokine release syndrome (CRS) and absence of neurotoxicity indicates a significant improvement over the other commercially approved CD19-directed CAR-T cell therapies. Dr Hasmukh Jain further reiterates, "NexCAR19 has shown an excellent balance of efficacy and low-toxicity, which is a significant advantage in clinical management (post-infusion) of the patients in our resource-constrained settings".

NexCAR19 is the culmination of a collaborative effort across a decade, between the IITBombay, and Tata Memorial Centre (TMC). Dr Atharva Karulkar, Dr Alka Dwivedi and the team led by Dr Rahul Purwar, Associate Professor at IIT Bombay designed and developed the NexCAR19, which subsequently underwent integrative process development & manufacturing under cGMP at ImmunoACT. Clinical investigations and translational studies were led by Dr Hasmukh Jain and Dr Gaurav Narula and their teams at TMH.

Reflecting on the successful completion of clinical trials, Dr Rahul Purwar, Founder & CEO of ImmunoACT says "This is like a dream come true and an incredible win for the patients in the country. Now our patients in India and countries with limited resources will have access to this life-saving drug at an affordable cost. In terms of technical achievement, this is comparable to the moon shot and it puts India on the elite list of select countries that have access to CAR-T therapy".

ImmunoACT is an IIT Bombay incubated company under the aegis of SINE (Society for Innovation and Entrepreneurship) and was founded in 2018 with the intention to be able to translate this academic research into a commercially viable product. As per Shirish Arya, Co-founder, and Director - Strategy & Business Development "ImmunoACT is now poised to become the country's leading multi-product, multi-service cell and gene therapy platform that can significantly change the paradigm of healthcare especially in the area of unmet needs".

Laurus Labs Limited which is a research-driven pharmaceutical and biotechnology company and has a global leadership position in select Active Pharmaceutical Ingredients (APIs) and has been the early backer of ImmunoACT and has invested over USD 18 million to support ImmunoACT to scale its R&D and commercialization efforts. Commenting on this important milestone, Dr Satyanarayana Chava, Founder-CEO of Laurus says "We are very happy and proud to be part of this indigenously developed Cell therapy product for Blood cancer treatment which will help cancer patients in India. This is a fast-evolving technology and we continue to back cutting-edge innovations in the space of cell and gene therapy and new drug discovery".

Tata Memorial Centre (TMC) Mumbai, is India's leading centre for cancer research and treatment center and has played a significant role in the Phase I and Phase II pivotal clinical trials. Dr Gaurav Narula, Professor- Pediatric Oncology, and Dr Hasmukh Jain, Professor - Medical Oncology and their team has been the partner for translational studies and clinical studies. Dr Gaurav Narula is the principal investigator (PI) of an investigator-initiated Phase II clinical trial in the pediatric population.

ImmunoACT intends to make the NexCAR19 (Actalycabtagene autoleucel) therapy available to its partner hospitals as soon as possible.

Shares of Laurus Labs Limited was last trading in BSE at Rs. 404.10 as compared to the previous close of Rs. 401.40. The total number of shares traded during the day was 56552 in over 1831 trades.

The stock hit an intraday high of Rs. 409.00 and intraday low of 399.00. The net turnover during the day was Rs. 22887138.00.


Click here to send ur comments or to feedback@equitybulls.com





Other Headlines:

MOIL Ltd announces price revision from Dec 1, 2023

Dixon Technologies' subsidiary Padget Electronics inaugurates New Manufacturing Plant in Noida

ITD Cementation India Ltd secures new order worth ~Rs 1,001 Crore

Wardwizard Innovations & Mobility Ltd and Triton EV forge strategic partnership for Electric Vehicle Manufacturing

SPIC shuts down plants for maintenance

YES SECURITIES elevates Mr. Anshul Arzare as MD&CEO and Mr. Amar Ambani as Executive Director

BLS International Opens a New State-of-the-art Visa Application Centre in Delhi

IDFC FIRST Private Banking and Hurun India release India's Top 200 Self-made Entrepreneurs of the Millennia 2023

Cipla partners with TEACH to create career opportunities for hearing-impaired youth

Mehai Technology Ltd wins orders from West Bengal Government

Himadri Speciality Chemical Ltd acquires Himadri Clean Energy Ltd

Kesoram Industries Ltd to demerge cement division into UltraTech Cement Ltd

IIFL Finance Raises JPY 7.5 billion from Mizuho Bank

Wipro Unveils 'Lab of the Future' with AWS to Transform Lab Processes

DAC accorded AONs for procurement of LCH & LCA Mk 1A and for upgradation of Su-30 MKI Aircraft

Beekay Niryat Ltd's associate company to expand capacity of Extra Neutral Alcohol

Cantabil Retail India Ltd opens 6 new showrooms in November 2023

LTIMindtree Partners with Metasphere to Deliver Smart Sewers Solutions

Sonata Software Ltd fixes Dec 12, 2023 as record date for 1:1 bonus issue

Kanoria Energy and Infrastructure Ltd approves investment of Rs. 300 crore

Primo Chemicals Ltd commences commercial production of Caustic Soda Flakes

Max Life's e-commerce channel achieves 55% YoY+ growth in H1 FY24

IndiaMART Wins Prestigious Gold Award from LACP for Second Consecutive Year

Delta Corp Ltd expands into the Real Estate sector

Biocon Biologics Successfully Completes Integration of Viatris' Biosimilar Business in 31 Countries in Europe

Infosys and Shell Collaborate on Immersion Cooling Services to Enable Sustainability-First Data Centers

MRF Ltd enters into captive power purchase agreement with First Energy 5 Pvt Ltd

Nitin Spinners Ltd commences commercial production in Ring Spinning Unit

Datamatics introduces TruCap+ Marketplace, speeding up the time-to-automation for Intelligent Document Processing by up to 70%

Crompton wins the prestigious 23rd Greentech Environment Award 2023 for its environmental commitment

Peninsula Land Limited's strong performance paves way for equity capital raise & joint venture

Tata Coffee Ltd announces capacity expansion in Vietnam

Shriram AMC Allots Equity Shares on Conversion of Securities for Mission1

SJVN Synchronizes Second Unit of Naitwar Mori HEP with National Grid

The Derma Co released its first purpose film on Young Scientists inviting people to join the mission

Uno Minda launches the new range of LED Blinkers in the Indian Aftermarket

Federal Bank announces strategic collaboration with NeML for Enhanced eProcurement and eAuction Integration

BW Confidence Enterprise Pvt Ltd and Ganesh Benzoplast Ltd to develop LPG Onshore Import Terminal at JNPT

Eugia Pharma receives USFDA Approval for Budesonide Inhalation Suspension, 0.5 mg/2 mL Single-Dose Ampule

SHREEJI enhances its presence with opening of new branch in Indore

Tata Tele Business Services Collaborates with Truecaller to offer 'Verified Business Caller ID Solution'

Integra Essentia Ltd receives order worth Rs. 120 million

Genesys International establishes Executive Innovation Board to propel India's First Comprehensive Map Stack

Best Airlines Rep selects 'AirGain to Provide Accurate Pricing Intelligence for Its Partner Airlines'

Confidence Petroleum India Ltd to raise Rs. 250 crores through preferential issue

DreamFolks strengthens its global presence through partnership with Grey Wall - one of Russia's leading lounge operator

Modi Naturals receives an order worth Rs ~230 crores from various OMCs for its ethanol division

Archit Organosys Ltd to form NOVEL AND NANO XTREME SOLUTIONS LLP for new business

PCBL Ltd to form JV with Kinaltek Pty Ltd

BW LPG's Significant Investment in Confidence Petroleum India Limited


Website Created & Maintained by : Chennai Scripts
West Mambalam, Chennai - 600 033,
Tamil Nadu, India

disclaimer copyright © 2005 - 2020